" Cure 4 AIDS Found?"

Doctors rid man of virus with bone marrow transplant"
Doctors have succeeded in ridding a man
of the HIV virus by giving him a bone marrow
transplant in what they claim is the closest
treatment yet to a cure for the disease.
The remarkable case gives new impetus to the
development of gene therapy for HIV which could
ultimately replace the need for expensive and
toxic antiretroviral drugs. Instead of taking
drugs for life, HIV sufferers might instead have
a one-off treatment that would leave them virus-free.
The 42-year-old American had been infected
with HIV for a decade. He was treated with
antiretroviral drugs in Berlin, where he
lives, for four years to hold the disease
in check, but then developed leukaemia.
Since being given a bone marrow transplant
two years ago, he has not taken antiretroviral
drugs to control HIV and has had no resurgence
of either disease. He is believed to be the
longest HIV-free survivor who was previously
treated with antiretroviral drugs.
Full details of the case were published for
the first time in The New England Journal of
Medicine.
An editorial in the journal says it
"places further emphasis on gene therapies" for
HIV, adding: "The case paves the way for innovative
approaches that provide long-lasting viral control
with limited toxicities for persons with HIV infection."
The man's treatment began with a search by doctors
at Berlin's Charité Hospital for a bone marrow donor
with a genetic resistance to HIV. One of the strangest
features of the disease is the way some people who have
been exposed to the virus on many occasions remain uninfected.
Twenty years ago, it was noticed that certain prostitutes
in Nairobi remained uninfected despite exposure to
the virus through thousands of sexual contacts.
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